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Dr. Angelov has a multifaceted clinical practice and research interests which focuses on the treatment of patients with metastatic brain tumors, primary malignant and benign tumors, spine radiosurgery and benign spine tumors. An important focus of her work is the development of the spine radiosurgery program at the Cleveland Clinic in 2006, the first clinical program of its kind in Ohio and indeed one of the earliest such programs in all of the U.S. This very active clinical program is now recognized globally.