Teaching Information
Teaching Schedule
Department of Nutrition, ӰƵ
- NTRN 454, Investigative methods in Nutritional Sciences, Course director
- NTRN, 455, Molecular Nutrition, Lecturer
School of Medicine, ӰƵ
- Block 3, “Food to Fuel”, co-leader and lecturer,
- Case Inquiry Facilitator, School of Medicine
Research Information
Research Interests
My research focuses on elucidating the mechanisms of observed metabolic phenotypes in patients with Cystic Fibrosis (CF) who commonly present with poor growth, nutritional deficiencies, elevated metabolic rate and others. We postulate that this apparent energy imbalance may be directly caused by the mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), primary cause of cystic fibrosis. To explore mechanisms of energy imbalance in CF patients, we use mouse models of cystic fibrosis that also exhibit growth retardation, elevated energy expenditure, and gastrointestinal and liver abnormalities. My research tools and technical expertise include liquid and gas chromatography mass spectrometry instrumentation (LC/MS-MS and GC/MS) and stable isotopic labeling. Using these modalities, we quantify changes in metabolic flux in a variety of biological models.
Additional Information
Dr. Bederman is a double Alumni from ӰƵ. He completed his undergraduate degree in Biochemistry (BA, 1998) followed by a PhD in Nutritional Biochemistry (2003, Department of Nutrition, advisor Henri Brunengraber, MD, PhD). He authored and co-authored 65 peer-reviewed publications including 7 in Nature journals and many conference abstracts in several key areas of nutrition and metabolism.