Professor
      
      Department of Ophthalmology and Visual Sciences
          School of Medicine
          Professor
      
      Department of Pathology
          School of Medicine
          Professor
      
      Department of Pharmacology
          School of Medicine
          Professor
      
      Hematology and Oncology
          Department of Medicine
      
      Professor
      
      Division of General Medical Sciences
          Professor
      
            Case Comprehensive Cancer Center
      
      My research includes cell death regulation, mechanism of epigenetic aging, the biological significance of DNA methylation age determining the timing of death, and the development of cell death inhibiting small compounds.
Primary appointment - Ophthalmology
Other appointments - Pharmacology, Pathology, General Medical Science, Case Comprehensive Cancer Center
Research Information
Research Interests
- Development of novel small compounds rescuing cells from mitochondria-dependent cell death
- The mechanism of epigenetic aging
- The development of the methods controlling aging and age-associated diseases.
- The mechanism of the inherited retinal dystrophies.
- Age-dependent corneal endothelial dystrophy.
Awards and Honors
Translational Research Acceleration Award
      
            2024
      
            Foundation Fighting Blindness
      
      Edmond S. Ricanati, MD Award
      
            2020
      
            ÐÓ°ÉÊÓÆµ
      
      Gund-Harrington Scholar Award 
      
            2017
      
            Foundation Fighting Blindness
      
      ASH Scholar Award
      
            2002
      
            American Society of Hematology
      
      Intergen Young Investigator Award
      
            2000
      
            American Association of Cancer Research 
      
      Bristol-Myers Squibb Young Investigator Award
      
            1999
      
            American Association of Cancer Research
      
      Veterinary Medical Science Scholar Award
      
            1994
      
            Japanese Society of Veterinary Science
      
      Kato memorial Award for Biological Research 
      
            1992
      
            Kato Memorial Foundation 
      
      Professional Memberships
Council Member, The Society of Experimental Biology and Medicine
              Member, The Association of Research in Vision and Ophthalmology
              Member, The International Society of Eye Research 
              Member, The American Society of Hematology
              Member, American Association of Cancer Research
          Publications
Education
BSc
      
            University of Tokyo
      
      Doctor of Veterinary Medicine
      
            University of Tokyo
      
      PhD
      
            University of Tokyo
      
      Postdoctoral Training
      
            The Burnham Institute (La Jolla Cancer Research Foundation)
      
      Additional Information
Service
- Associate Editor (Aging Section), Experimental Biology of Medicine
- Section Editor (Cancer Research), Science Progress
- Editorial Board member (Cell Biology section), Cells
