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CWRU receives third-straight $500,000 technology start-up fund award from Ohio Third Frontier Commission

FEATURED | January 16, 2019
STORY BY: EDITORIAL STAFF

Only Ohio institution to receive funding all three years

The has awarded 杏吧视频 its third $500,000 grant since 2016 for the CWRU Technology Validation and Start-Up Fund Program (CTP), a campus-based translational research fund to help faculty researchers advance and commercialize their innovations. The next round of funding for CTP will be offered this spring. (See more information about the fund.) In the CTP鈥檚 first two years, 70 letters of intent were submitted, 49 full proposals were reviewed and 19 projects were funded. Each proposal was vetted by an external selection committee, with 19 projects ultimately selected for funding. To date, more than $12 million in 鈥渇ollow-on鈥 funding has been attracted to these funded projects, with two funded projects already licensed to university startups. 鈥淚nvestigators at CWRU have brought a number of projects to the cusp of commercial readiness, and this program, in combination with our experienced team of internal and external advisors, is designed specifically to take these projects to the next level,鈥 said Michael Haag, the Technology Transfer Office鈥檚 executive director for technology management and principal investigator for the state grant for the university鈥檚 Technology Transfer Office (TTO). 鈥淭he quality of our research and our commercialization team stands out on a state and national level.鈥 鈥淲e are grateful that the state has recognized the unique capabilities of CWRU to commercialize its technologies and make CWRU the only Ohio institution to receive this start-up fund award each of the last three years,鈥 said Stephanie Weidenbecher, a TTO senior licensing manager who directs the CTP program. Ohio Third Frontier was created in 2002 to build a statewide system that moves technology and innovation from the laboratory to the marketplace. This program, created in 2012, awards money to support technologies developed at Ohio research institutions and spin-off companies that license the technologies. The fund focuses especially on driving development in:
  • Biomedical/life sciences;
  • Advanced materials;
  • Sensors;
  • Energy;
  • Advanced Manufacturing; and
  • Software/information technology.
Since the program鈥檚 inception in 2012, the Ohio Third Frontier Commission has funded a total of 32 杏吧视频 projects. These projects have attracted more than $30 million in follow-on funding; five of which have been licensed to university startups. CTP recently announced the recipients of its third and final funding round of 2018:

Principal investigator: , assistant professor in the Department of Mechanical & Aerospace Engineering at the Case School of Engineering

Project: Interactive block games for routine cognitive assessment of older adults at high risk of Alzheimer's disease Lee received the award for an automated, cube game-based diagnostic for mild cognitive impairment (MCI) and early Alzheimer鈥檚 disease (AD) in older adults. Current diagnostic techniques for MCI and AD require administration and analysis by specialized health care professionals. Lee鈥檚 technology reduces costs and eliminates subjectivity of these current techniques.

Principal investigator: , assistant professor in the Department of Biomedical Engineering at the Case School of Engineering    

Project: BG34-200: A potent immunotherapeutic for melanoma, osteosarcoma and other solid tumor cancers Zhang received the award for an immunotherapeutic that has demonstrated efficacy in vivo in a number of aggressive solid tumor cancers with unmet clinical needs. Zhang鈥檚 immunotherapeutic stimulates the immune system through a novel mechanism of action to traverse the normally immunosuppressive tumor microenvironment and attack tumor cancer cells.

Principal investigator: James Basilion, professor in the Department of Radiology at the School of Medicine

Project: Targeted microtubule disruption agents for prostate cancer Basilion received the award for a chemotherapeutic that binds a known prostate cancer biomarker and has demonstrated proof-of-concept in prostate cancer animal models. As this biomarker is expressed in prostate cancers that are refractory for all currently approved therapeutics, this novel chemotherapeutic may meet a significant unmet clinical need.

Principal investigator: , professor in the Department of Biomedical Engineering at CSE     

Project: Clinical evaluation of a self-leveling walker Triolo received the award for a four-legged walker suitable for uneven surfaces like ramps or stairs. Walker-dependent geriatric and orthopedic patients often confront curbs, steps and ramps that they are unable to negotiate using currently available assistive devices. Often, the inability to safely negotiate stairs is the single limiting factor to delay discharge to home, which extends stays in rehabilitation settings or require expensive architectural changes to the home environment.
For more information, contact Bill Lubinger at william.lubinger@case.edu