Block 1 - Becoming a Doctor
- Analyze, critique and present research studies from the primary literature.
- Apply a framework for social, behavioral, structural, and environmental determinants of health to patient care and population health.
- Demonstrate habits of ongoing reflection to identify learning needs, increase self-awareness, and continuously improve performance and personal growth.
- Develop and practice the knowledge and skills that promote effective teamwork across a variety of settings.
- Explore professional values and career paths to create a foundation for professional identity development.
- Illustrate effective means to measure, understand, and affect the health of populations.
- Link domains of Health System Science in health care structure, policy, value and economics, health systems improvement, and health informatics.
- Recognize and analyze ethical problems in clinical medicine and biomedical research employing a variety of approaches including use of the principles of justice, nonmaleficence, beneficence, and respect for autonomy as a guiding framework.
- Understand and demonstrate effective communication skills for learning and clinical practice environments.
- Understand and practice the behaviors of an ethical, respectful, compassionate, reliable, and responsible physician.
- Utilize a framework for implementation of bioethical principles in the practice of public health, population health, health systems science and clinical medicine.
- Utilize principles of epidemiology and biostatistics to interpret scientific literature and clinical cases.
Block 2 - The Human Blueprint
- Analyze, critique and present research studies from the primary literature.
- Demonstrate habits of ongoing reflection to identify learning needs, increase self-awareness, and continuously improve performance and personal growth.
- Develop and practice the knowledge and skills that promote effective teamwork across a variety of settings.
- Recognize and analyze ethical problems in clinical medicine and biomedical research employing a variety of approaches including use of the principles of justice, nonmaleficence, beneficence, and respect for autonomy as a guiding framework.
- Understand and demonstrate effective communication skills for learning and clinical practice environments.
- Understand and practice the behaviors of an ethical, respectful, compassionate, reliable, and responsible physician.
- Understand cancer treatment options including surgery and radiation cytotoxic chemotherapy targeted therapies including those based on monoclonal antibodies and small molecules, as well as their modes of action.
- Understand how DNA sequence alterations and epigenetic changes, defects in DNA repair pathways and dysregulation of signal transduction pathways lead to cancer, as well as the impact of cancer on public health.
- Understand human reproduction including male and female gametogenesis, neuroendocrine control of sexual development, hormonal control of pregnancy and parturition and methods of contraception.
- Understand the basic mechanisms of DNA replication and transcription including the impact of chromatin structure and epigenetic marks as well as the roles of cis-acting signals and trans-acting factors.
- Understand the genetic basis and inheritance patterns (traditional and non-traditional) that lead to disease states including congenital defects and cancer; these include the consequences of mis-segregation of entire chromosomes, insertions, or deletions of portions of chromosomes, and point mutations that affect single genes.
- Understand the mechanisms through which gene expression is regulated at multiple steps including transcription, RNA processing and translation and the impact of mutations that lead to disease due to faulty regulation.
- Understand the normal development of a human embryo and describe how it is altered in developmental disorders that result from mutations or environmental factors.
- Understand the normal synthesis, targets, regulation, and mechanisms of action of hormones and the molecular, cellular and tissue changes that accompany diseases that result from dysregulation of hormone production or targeting.
- Understand the principles and pathways of signal transduction and how disruption of intra- or intercellular communication leads to diseases including endocrine disorders and cancer.
- Understand the technical advances that led to the development of personalized medicine and describe how the results of genetic tests can be used to assess prognosis and treatment options for a growing number of diseases including congenital defects and cancer.
Block 3 - Food to Fuel
- Analyze, critique and present research studies from the primary literature.
- Demonstrate habits of ongoing reflection to identify learning needs, incr