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Case Comprehensive Cancer Center

Associate Directors' Message: Creating solutions to address cancer disparities
Dear Members of the Cancer Center community, Next month, on March 4-5, we are hosting the 5th Annual Cancer Disparities Symposium, themed as “Navigating Cancer Disparities: Lessons Learned and How to Move Forward.” This symposium has attracted a diverse audience as we will not only be joined by sci...
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Study Shows Machine Learning’s Potential to Predict Cancer Therapy-Related Cardiac Risk
From Cleveland Clinic Lerner Research Institute: Machine learning-based approaches to risk assessment can be highly effective in predicting various types of cardiac dysfunction among cancer survivors who have received cardiotoxic cancer therapies, according to a new retrospective longitudinal study ...
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Chakraborty awarded 2020 V Scholar Grant
The Case Comprehensive Cancer Center extends congratulations to Cleveland Clinic's Abhishek Chakraborty, PhD as he was awarded a 2020 V Scholar Grant from the V Foundation for Cancer Research for his proposal, "Chromatin Dysfunction Identifies Metabolic Regulators as Potential Therapeutic Targets in...
Colorectal cancer research funded by the National Cancer Institute investigates new potential immunotherapy targets
A team of researchers from CWRU and UH is investigating the role of Erbb3 in the development of colorectal cancer. To put it simply, says lead investigator Zhenghe John Wang, PhD, the team is attempting to discover the pathways that can switch the cold tumors to hot tumors, and activate immune check...
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Scientists design 3D model of molecule key to halting tumor growth
Research into stopping tumor growth was recently featured in BBC Science Focus Magazine as one of the world's "20 moments in 2020 to be excited about." A compound that activates an enzyme capable of suppressing tumors was discovered by a cross-institutional team from the University of Michigan and C...
Potential new target for treating chemotherapy-associated kidney damage
From Cleveland Clinic Lerner Research Institute: Standard-of-care treatment for many cancers includes chemotherapy drug cisplatin which prevents the spread of cancer cells by interrupting DNA replication and damaging the genetic material in rapidly dividing tumor cells. Unfortunately, the drug can c...
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First glioblastoma patient dosed with Phase 2 trial at UH Seidman Cancer Center testing PVSRIPO plus Keytruda
Glioblastoma, recognized as the most aggressive primary brain cancer in adults is also known to be among the most immunosuppressive of tumors. A Phase 2 clinical trial of PVSRIPO, a revolutionary viral immunotherapy for cancer treatment, in combination with Keytruda (pembrolizumab) is underway acros...
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Concurrent chemotherapy and antibiotic use associated with epithelial ovarian cancer outcomes
Researchers at Cleveland Clinic's Ob/Gyn & Women's Health Institute and Lerner Research Institute recently published a retrospective study in Gynecologic Oncology which found that women with newly diagnosed stage III or IV epithelial ovarian cancer and received antibiotics following cytoreductive su...
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Brawley, McCaskill-Stevens headline 5th Annual Cancer Disparities Symposium
Case Comprehensive Cancer Center is once again hosting the Cancer Disparities Symposium, March 4-5, 2021. The symposium will take place virtually due to COVID restrictions. However, attendees can expect the same level of high-caliber research and an overall dedication to conquering health disparitie...
Northeast Ohio leaders in healthcare and higher education partner with State, announce historic investment in Cleveland Innovation District
Ohio Governor Mike DeWine and Lt. Governor Jon Husted on Monday announced the Cleveland Innovation District, a transformational collaboration of Northeast Ohio's leading healthcare and higher education institutions. The Cleveland Innovation District brings together ӰƵ, ...